Ergot: Difference between revisions
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[[File:Ergoline.png|right|thumb|The ergoline skeleton looks not entirely unlike a cock-n-balls.]] | [[File:Ergoline.png|right|thumb|The ergoline skeleton looks not entirely unlike a cock-n-balls.]] | ||
Ergot is pronounced ur-git, '''not''' er-go. Highly toxic, it ought not be consumed. Properly modified, it has many uses, primarily due to fortuitous similarity between the ergoline skeleton and the monoamide neurotransmitters (e.g. serotonin, dopamine, | Ergot is pronounced ur-git, '''not''' er-go. Highly toxic, it ought not be consumed. Properly modified, it has many uses, primarily due to fortuitous similarity between the ergoline skeleton and the monoamide neurotransmitters (e.g. serotonin, dopamine, noradrenaline)... | ||
Ergot alkaloids ergonovine and ergotamine (and their salts) are both original List I controlled precursors under the [https://en.wikipedia.org/wiki/Controlled_Substances_Act 1970 Controlled Substances Act]. Ergocristine was added to List I in 2010 (see the DEA's 2010-03 ''[https://www.erowid.org/library/periodicals/microgram/microgram_2010-03.pdf Microgram Journal]''). Derivatives lysergic acid and its amide ("ergine") are Schedule III controlled substances under the CSA, and ergine is a Class A precursor in the United Kingdom. Subsequent derivative lysergic acid diethylamide is an original Schedule I controlled substance, and its functional analogues (any chemical "substantially similar", as if that had any kind of precise meaning) are treated as Schedule I due to the [https://en.wikipedia.org/wiki/Federal_Analogue_Act 1986 Federal Analogue Act]. Ergotamine, lysergic acid, and ergometrine (ergonovine) are all on Table I of the INCB Red List, and are thus EU Category 1 precursors. So there's clearly something worth knowing about ergot! | Ergot alkaloids ergonovine and ergotamine (and their salts) are both original List I controlled precursors under the [https://en.wikipedia.org/wiki/Controlled_Substances_Act 1970 Controlled Substances Act]. Ergocristine was added to List I in 2010 (see the DEA's 2010-03 ''[https://www.erowid.org/library/periodicals/microgram/microgram_2010-03.pdf Microgram Journal]''). Derivatives lysergic acid and its amide ("ergine") are Schedule III controlled substances under the CSA, and ergine is a Class A precursor in the United Kingdom. Subsequent derivative lysergic acid diethylamide is an original Schedule I controlled substance, and its functional analogues (any chemical "substantially similar", as if that had any kind of precise meaning) are treated as Schedule I due to the [https://en.wikipedia.org/wiki/Federal_Analogue_Act 1986 Federal Analogue Act]. Ergotamine, lysergic acid, and ergometrine (ergonovine) are all on Table I of the INCB Red List, and are thus EU Category 1 precursors. So there's clearly something worth knowing about ergot! | ||