Ergot: Difference between revisions
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==Ergoline path (the ergot alkaloids)== | ==Ergoline path (the ergot alkaloids)== | ||
* L-Tryptophan -> (prenylation via DMAPP from mevalonic acid, catalyzed by DMATS) | * L-Tryptophan C<sub>11</sub>H<sub>12</sub>N<sub>2</sub>O<sub>2</sub> -> (prenylation via DMAPP from mevalonic acid, catalyzed by DMATS) | ||
** DMAT(S): dimethylallyltryptophan (synthetase) | |||
* 4-L-DMAT -> (N-methylation via SAM, catalyzed by EasF) | * 4-L-DMAT -> (N-methylation via SAM, catalyzed by EasF) | ||
* 4-DMA-L-abrine -> (decarboxylation+oxidation via EasC, catalyzed by EasE) | * 4-DMA-L-abrine -> (decarboxylation+oxidation via EasC, catalyzed by EasE) | ||