Ergot

Line 138:

==tl;dr==

My opinion is that modern LSD manufacture, barring connections to the Chinese or Indian underworlds or a few acres of toxified rye, is best accomplished via controlled biosynthesis of DLA in yeasts followed by DLA conversion in a microreactor array. Extraction and hydrolysis of alkaloids from a broth of petri-grown ergot is also completely feasible, and easily scaled to kilograms. You do not need a megagram of LSD (you probably don't need a kilogram). Either way, the chemistry is not complex, but it does require precision, patience, and a significant investment in equipment. Making effective use of precursors requires multiple rounds, as does purification of the single psychoactive stereoisomer. Performing these tedious rounds while avoiding accidental exposure is perhaps the most difficult practical aspect of manufacture.

My opinion is that modern LSD manufacture, barring connections to the Chinese or Indian underworlds or a few acres of toxified rye, is best accomplished via controlled biosynthesis of DLA in yeasts followed by DLA conversion in a microreactor array. Extraction and hydrolysis of alkaloids from a broth of petri-grown ergot is also completely feasible, and easily scaled to kilograms. You do not need a megagram of LSD (you probably don't need a kilogram). Either way, the chemistry is not complex, but it does require precision, patience, a solid few days without interruption, and a significant investment in equipment. Making effective use of precursors requires multiple rounds, as does purification of the single psychoactive stereoisomer. Performing these tedious rounds while avoiding accidental exposure is perhaps the most difficult practical aspect of manufacture.

Isolsd and lumalsd are not psychoactive, but seem to put equal stress on the body otherwise. Raising the unit dosage to compensate for an impure result will deliver more of these undesirable contaminants. Good product '''requires repeated conversion of stereoisomers'''.

Ergot: Difference between revisions

Dank (talk | contribs)

@@ Line 138: / Line 138: @@
 ==tl;dr==
-My opinion is that modern LSD manufacture, barring connections to the Chinese or Indian underworlds or a few acres of toxified rye, is best accomplished via controlled biosynthesis of DLA in yeasts followed by DLA conversion in a microreactor array. Extraction and hydrolysis of alkaloids from a broth of petri-grown ergot is also completely feasible, and easily scaled to kilograms. You do not need a megagram of LSD (you probably don't need a kilogram). Either way, the chemistry is not complex, but it does require precision, patience, and a significant investment in equipment. Making effective use of precursors requires multiple rounds, as does purification of the single psychoactive stereoisomer. Performing these tedious rounds while avoiding accidental exposure is perhaps the most difficult practical aspect of manufacture.
+My opinion is that modern LSD manufacture, barring connections to the Chinese or Indian underworlds or a few acres of toxified rye, is best accomplished via controlled biosynthesis of DLA in yeasts followed by DLA conversion in a microreactor array. Extraction and hydrolysis of alkaloids from a broth of petri-grown ergot is also completely feasible, and easily scaled to kilograms. You do not need a megagram of LSD (you probably don't need a kilogram). Either way, the chemistry is not complex, but it does require precision, patience, a solid few days without interruption, and a significant investment in equipment. Making effective use of precursors requires multiple rounds, as does purification of the single psychoactive stereoisomer. Performing these tedious rounds while avoiding accidental exposure is perhaps the most difficult practical aspect of manufacture.
 Isolsd and lumalsd are not psychoactive, but seem to put equal stress on the body otherwise. Raising the unit dosage to compensate for an impure result will deliver more of these undesirable contaminants. Good product '''requires repeated conversion of stereoisomers'''.